LRRN2 rabbit pAb
- Catalog No.:YT7610
- Applications:WB;ELISA;IHC
- Reactivity:Human
- Target:
- LRRN2
- Gene Name:
- LRRN2 GAC1 LRRN5 UNQ256/PRO293
- Protein Name:
- LRRN2
- Human Gene Id:
- 10446
- Human Swiss Prot No:
- O75325
- Immunogen:
- Synthesized peptide derived from human LRRN2 AA range: 296-346
- Specificity:
- This antibody detects endogenous levels of LRRN2 at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 78kD
- Background:
- The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],
- Function:
- similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,tissue specificity:Overamplified in malignant gliomas.,
- Subcellular Location:
- Membrane ; Single-pass type I membrane protein .
- Expression:
- Overamplified in malignant gliomas.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).