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- TULP3 rabbit pAb
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TULP3 rabbit pAb
- Catalog No.:YT7270
- Applications:WB
- Reactivity:Human;Mouse
- Immunogen:
- Synthesized peptide derived from human TULP3 AA range: 257-307
- Specificity:
- This antibody detects endogenous levels of TULP3 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 49kD
- Background:
- This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009],
- Function:
- similarity:Belongs to the TUB family.,tissue specificity:Expressed at high levels in testis, ovaries, thyroid, and spinal chord.,
- Subcellular Location:
- Nucleus. Cell membrane. Cell projection, cilium . Cytoplasm . Secreted . Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. .
- Expression:
- Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
![](/uploadfiles/PIC/YT7270wb-2019.jpg)
- Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night