• Target：
• TULP3

• Gene Name：
• TULP3 TUBL3

• Protein Name：
• TULP3

• Human Gene Id：
• 7289

• Human Swiss Prot No：
• O75386

• Mouse Gene Id：
• 22158

• Mouse Swiss Prot No：
• O88413

• Immunogen：
• Synthesized peptide derived from human TULP3 AA range: 257-307

• Specificity：
• This antibody detects endogenous levels of TULP3 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 49kD

• Background：
• This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009],

• Function：
• similarity:Belongs to the TUB family.,tissue specificity:Expressed at high levels in testis, ovaries, thyroid, and spinal chord.,

• Subcellular Location：
• Nucleus. Cell membrane. Cell projection, cilium . Cytoplasm . Secreted . Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. .

• Expression：
• Expressed at high levels in testis, ovaries, thyroid, and spinal chord.

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