• Target：
• DBC1

• Gene Name：
• DBC1 DBCCR1 FAM5A IB3089A

• Protein Name：
• DBC1

• Human Gene Id：
• 1620

• Human Swiss Prot No：
• O60477

• Mouse Gene Id：
• 56710

• Mouse Swiss Prot No：
• Q920P3

• Rat Gene Id：
• 140610

• Rat Swiss Prot No：
• Q925T8

• Immunogen：
• Synthesized peptide derived from human DBC1 AA range: 100-150

• Specificity：
• This antibody detects endogenous levels of DBC1 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 84kD

• Background：
• This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq, Jul 2008],

• Function：
• function:Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.,miscellaneous:DBC1 is silenced by methylation in 50% of bladder cancer cell lines.,similarity:Belongs to the FAM5 family.,similarity:Contains 1 MACPF domain.,tissue specificity:Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.

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