KR131 rabbit pAb

    • Catalog No.:YT7150
    • Applications:WB;ELISA;IHC
    • Reactivity:Human
      • Target:
      • KR131
      • Gene Name:
      • KRTAP13-1 KAP13.1 KRTAP13.1
      • Protein Name:
      • KR131
      • Human Swiss Prot No:
      • Q8IUC0
      • Immunogen:
      • Synthesized peptide derived from human KR131 AA range: 99-149
      • Specificity:
      • This antibody detects endogenous levels of KR131 at Human
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 19kD
      • Background:
      • Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008],
      • Function:
      • caution:The sequence of 1-41 of PubMed:12359730 has not been submitted.,function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the PMG family.,subunit:Interacts with hair keratins.,tissue specificity:Weak expression seen in the late matrix and entire cortex area of the hair follicle.,
      • Subcellular Location:
      • intermediate filament,
      • Expression:
      • Weak expression seen in the late matrix and entire cortex area of the hair follicle.
      • Products Images
      • Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).