• Target：
• TYDP2

• Gene Name：
• TDP2 EAP2 TTRAP AD-022

• Protein Name：
• TYDP2

• Human Gene Id：
• 51567

• Human Swiss Prot No：
• O95551

• Mouse Gene Id：
• 56196

• Mouse Swiss Prot No：
• Q9JJX7

• Rat Gene Id：
• 498749

• Rat Swiss Prot No：
• Q3T1H5

• Immunogen：
• Synthesized peptide derived from human TYDP2 AA range: 261-311

• Specificity：
• This antibody detects endogenous levels of TYDP2 at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 40kD

• Background：
• This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008],

• Subcellular Location：
• Nucleus . Nucleus, PML body . Nucleus, nucleolus . Cytoplasm. Localizes to nucleolar cavities following stress; localization to nucleolus is dependent on PML protein. .; Cytoplasm . (Microbial infection) In case of infection by picornavirus, relocalizes to cytoplasmic sites distinct from those containing viral proteins associated with RNA replication or encapsidation. .

• Expression：
• Widely expressed (PubMed:10764746). Highly expressed in various brain regions, including the frontal and occipital lobes, the hippocampus, the striatum and the cerebellum (PubMed:24658003).

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