• Target：
• XPO6

• Fields：
• >>Nucleocytoplasmic transport

• Gene Name：
• XPO6 KIAA0370 RANBP20

• Protein Name：
• XPO6

• Human Gene Id：
• 23214

• Human Swiss Prot No：
• Q96QU8

• Mouse Gene Id：
• 74204

• Mouse Swiss Prot No：
• Q924Z6

• Immunogen：
• Synthesized peptide derived from human XPO6 AA range: 204-254

• Specificity：
• This antibody detects endogenous levels of XPO6 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 124kD

• Background：
• The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012],

• Function：
• function:Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.,similarity:Belongs to the exportin family.,similarity:Contains 1 importin N-terminal domain.,subcellular location:Shuttles between the nucleus and the cytoplasm.,subunit:Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with ACTB. Interacts with ACTB in a RanGTP-dependent manner.,

• Subcellular Location：
• Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm. .

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