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- BHE22 rabbit pAb
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BHE22 rabbit pAb
- Catalog No.:YT6964
- Applications:WB
- Reactivity:Human;Mouse
- Gene Name:
- BHLHE22 BHLHB5 TNRC20
- Immunogen:
- Synthesized peptide derived from human BHE22 AA range: 243-293
- Specificity:
- This antibody detects endogenous levels of BHE22 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 42kD
- Background:
- This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. A similar protein in mouse is required for the development of the dorsal cochlear nuclei, and is thought to play a role in in the differentiation of neurons involved in sensory input. The mouse protein also functions in retinogenesis. [provided by RefSeq, Oct 2016],
- Function:
- function:Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,tissue specificity:Brain-specific, with the highest expression in the cerebellum.,
- Subcellular Location:
- Nucleus .
- Expression:
- Brain-specific, with the highest expression in the cerebellum.
![](/uploadfiles/PIC/YT6964wb-2019.jpg)
- Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night