• Target：
• FXL12

• Gene Name：
• FBXL12 FBL12

• Protein Name：
• FXL12

• Human Gene Id：
• 54850

• Human Swiss Prot No：
• Q9NXK8

• Mouse Gene Id：
• 30843

• Mouse Swiss Prot No：
• Q9EPX5

• Immunogen：
• Synthesized peptide derived from human FXL12 AA range: 8-58

• Specificity：
• This antibody detects endogenous levels of FXL12 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 36kD

• Background：
• Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],

• Function：
• function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with SKP1A and CUL1.,

• Subcellular Location：
• ubiquitin ligase complex,cytoplasm,integral component of membrane,

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