- Home
- About
- Promotions
-
Products
-
Elisa Kits
- |
-
Primary antibodies
- |
-
Secondary antibodies
- |
-
Proteins
- |
-
IHC reagents
- |
-
WB reagents
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
- News
- Distributor
- Resources
- Contact
- Home
- >
- Info
- >
- FXL12 rabbit pAb
- >
- Go Back
FXL12 rabbit pAb
- Catalog No.:YT6954
- Applications:WB
- Reactivity:Human;Mouse
- Immunogen:
- Synthesized peptide derived from human FXL12 AA range: 8-58
- Specificity:
- This antibody detects endogenous levels of FXL12 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 36kD
- Background:
- Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],
- Function:
- function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with SKP1A and CUL1.,
- Subcellular Location:
- ubiquitin ligase complex,cytoplasm,integral component of membrane,
![](/uploadfiles/PIC/YT6954wb-2019.jpg)
- Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night