BEX2 rabbit pAb

    • Catalog No.:YT6847
    • Applications:WB
    • Reactivity:Human;Mouse;Rat
      • Target:
      • BEX2
      • Gene Name:
      • BEX2
      • Protein Name:
      • BEX2
      • Human Swiss Prot No:
      • Q9BXY8
      • Mouse Swiss Prot No:
      • Q9WTZ8
      • Immunogen:
      • Synthesized peptide derived from human BEX2 AA range: 28-78
      • Specificity:
      • This antibody detects endogenous levels of BEX2 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 14kD
      • Background:
      • This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
      • Function:
      • caution:Was named BEX1 by some authors.,similarity:Belongs to the BEX family.,subunit:Interacts with OMP (By similarity). Interacts with LMO2, possibly leading to regulate the transcriptional activity of a DNA-binding complex containing LMO2.,tissue specificity:Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe.,
      • Subcellular Location:
      • Cytoplasm . Nucleus .
      • Expression:
      • Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines.
      • Products Images
      • Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night