GFPT1 rabbit pAb
- Catalog No.:YT6792
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- GFPT1
- Fields:
- >>Alanine, aspartate and glutamate metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of nucleotide sugars;>>Insulin resistance;>>Diabetic cardiomyopathy
- Gene Name:
- GFPT1 GFAT GFPT
- Protein Name:
- GFPT1
- Human Gene Id:
- 2673
- Human Swiss Prot No:
- Q06210
- Mouse Gene Id:
- 14583
- Mouse Swiss Prot No:
- P47856
- Rat Gene Id:
- 297417
- Rat Swiss Prot No:
- P82808
- Immunogen:
- Synthesized peptide derived from human GFPT1 AA range: 198-248
- Specificity:
- This antibody detects endogenous levels of GFPT1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 77kD
- Background:
- This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008],
- Function:
- catalytic activity:L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.,function:Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.,pathway:Nucleotide-sugar biosynthesis; UDP-N-acetyl-D-glucosamine biosynthesis; D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.,similarity:Contains 1 glutamine amidotransferase type-2 domain.,similarity:Contains 2 SIS domains.,subunit:Homotetramer .,tissue specificity:Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.,
- Subcellular Location:
- cytosol,extracellular exosome,
- Expression:
- Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night