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- CE120 rabbit pAb
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CE120 rabbit pAb
- Catalog No.:YT6616
- Applications:WB
- Reactivity:Human;Mouse
- Gene Name:
- CEP120 CCDC100
- Immunogen:
- Synthesized peptide derived from human CE120 AA range: 335-385
- Specificity:
- This antibody detects endogenous levels of CE120 at Human/Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 108kD
- Background:
- This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
- Function:
- function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors.,similarity:Belongs to the CEP120 family.,subcellular location:Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.,subunit:Interacts with TACC2 and TACC3.,
- Subcellular Location:
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. .
![](/uploadfiles/PIC/YT6616wb-2019.jpg)
- Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night