• Target：
• CE120

• Gene Name：
• CEP120 CCDC100

• Protein Name：
• CE120

• Human Gene Id：
• 153241

• Human Swiss Prot No：
• Q8N960

• Mouse Gene Id：
• 225523

• Mouse Swiss Prot No：
• Q7TSG1

• Immunogen：
• Synthesized peptide derived from human CE120 AA range: 335-385

• Specificity：
• This antibody detects endogenous levels of CE120 at Human/Mouse

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 108kD

• Background：
• This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

• Function：
• function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors.,similarity:Belongs to the CEP120 family.,subcellular location:Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.,subunit:Interacts with TACC2 and TACC3.,

• Subcellular Location：
• Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. .

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