GLDN rabbit pAb
- Catalog No.:YT6545
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- GLDN
- Gene Name:
- GLDN COLM UNQ9339/PRO34011
- Protein Name:
- GLDN
- Human Gene Id:
- 342035
- Human Swiss Prot No:
- Q6ZMI3
- Mouse Gene Id:
- 235379
- Mouse Swiss Prot No:
- Q8BMF8
- Rat Gene Id:
- 315675
- Rat Swiss Prot No:
- Q80WL1
- Immunogen:
- Synthesized peptide derived from human GLDN AA range: 461-511
- Specificity:
- This antibody detects endogenous levels of GLDN at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 61kD
- Function:
- domain:The olfactomedin-like domain mediates NFASC/neurofascin and NRCAM binding.,function:Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier.,similarity:Contains 1 olfactomedin-like domain.,similarity:Contains 2 collagen-like domains.,subcellular location:Localizes to the nodes of Ranvier.,subunit:Interacts with NFASC/neurofascin and NRCAM.,tissue specificity:Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.,
- Subcellular Location:
- Cell membrane ; Single-pass type II membrane protein . Cell projection, axon . Detected at the nodes of Ranvier. Detected at immature heminodes. .; [Gliomedin shedded ectodomain]: Secreted . Secreted, extracellular space, extracellular matrix . Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier. .
- Expression:
- Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night