CNDH2 rabbit pAb

    • Catalog No.:YT6517
    • Applications:WB
    • Reactivity:Human;Mouse;Rat
      • Target:
      • CNDH2
      • Gene Name:
      • NCAPH2 CAPH2
      • Protein Name:
      • CNDH2
      • Human Swiss Prot No:
      • Q6IBW4
      • Mouse Swiss Prot No:
      • Q8BSP2
      • Immunogen:
      • Synthesized peptide derived from human CNDH2 AA range: 501-551
      • Specificity:
      • This antibody detects endogenous levels of CNDH2 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 67kD
      • Background:
      • This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010],
      • Function:
      • function:Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CND2 H2 (condensin-2 subunit 2) family.,subcellular location:Distributed along the arms of chromosomes assembled in vivo and in vitro.,subunit:Component of the condensin-2 complex, which contains the smc2 and smc4 heterodimer, and three non SMC subunits, ncapg2, ncaph2 and ncapd3 that probably regulate the complex.,
      • Subcellular Location:
      • Nucleus . Chromosome . Distributed along the arms of chromosomes assembled in vivo and in vitro.
      • Products Images
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night