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- BRD1 rabbit pAb
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BRD1 rabbit pAb
- Catalog No.:YT6310
- Applications:WB
- Reactivity:Human;Mouse
- Gene Name:
- BRD1 BRL BRPF2
- Immunogen:
- Synthesized peptide derived from human BRD1 AA range: 399-449
- Specificity:
- This antibody detects endogenous levels of BRD1 at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 116kD
- Background:
- This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],
- Function:
- function:Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.,similarity:Contains 1 bromo domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Component of the MOZ/MORF composed at least of ING5, MYST3/MOZ, MYST4/MORF and one of BRPF1, BRD1/BRPF2 and BRPF3.,tissue specificity:Highly expressed in testis.,
- Subcellular Location:
- Nucleus . Chromosome . Localizes to transcription start sites. .
- Expression:
- Highly expressed in testis.
![](/uploadfiles/PIC/YT6310wb-2019.jpg)
- Western blot analysis of lysates from CACO2 cells, primary antibody was diluted at 1:1000, 4°over night