• Target：
• IL-17F

• Fields：
• >>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway;>>Th17 cell differentiation;>>Inflammatory bowel disease

• Gene Name：
• IL17F IL24

• Protein Name：
• Interleukin-17F (IL-17F) (Cytokine ML-1) (Interleukin-24) (IL-24)

• Human Gene Id：
• 112744

• Human Swiss Prot No：
• Q96PD4

• Mouse Gene Id：
• 257630

• Mouse Swiss Prot No：
• Q7TNI7

• Immunogen：
• Synthetic peptide from human protein at AA range: 81-130

• Specificity：
• The antibody detects endogenous IL-17F

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Interleukin-17F (IL-17F;Cytokine ML-1;Interleukin-24;IL-24)

• Background：
• The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008],

• Function：
• function:Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.,

• Subcellular Location：
• Secreted .

• Expression：
• Expressed in T-helper 1 and T-helper 2 cells, basophils and mast cells.

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