IL-17F Polyclonal Antibody
- Catalog No.:YT6047
- Applications:IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- IL-17F
- Fields:
- >>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway;>>Th17 cell differentiation;>>Inflammatory bowel disease
- Gene Name:
- IL17F IL24
- Protein Name:
- Interleukin-17F (IL-17F) (Cytokine ML-1) (Interleukin-24) (IL-24)
- Human Gene Id:
- 112744
- Human Swiss Prot No:
- Q96PD4
- Mouse Gene Id:
- 257630
- Mouse Swiss Prot No:
- Q7TNI7
- Immunogen:
- Synthetic peptide from human protein at AA range: 81-130
- Specificity:
- The antibody detects endogenous IL-17F
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Interleukin-17F (IL-17F;Cytokine ML-1;Interleukin-24;IL-24)
- Background:
- The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008],
- Function:
- function:Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.,
- Subcellular Location:
- Secreted .
- Expression:
- Expressed in T-helper 1 and T-helper 2 cells, basophils and mast cells.
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