CDNF Polyclonal Antibody
- Catalog No.:YT5969
- Applications:IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- CDNF
- Gene Name:
- CDNF ARMETL1
- Protein Name:
- Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor)
- Human Gene Id:
- 441549
- Human Swiss Prot No:
- Q49AH0
- Mouse Gene Id:
- 227526
- Mouse Swiss Prot No:
- Q8CC36
- Immunogen:
- Synthetic peptide from human protein at AA range: 31-80
- Specificity:
- The antibody detects endogenous CDNF
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Cerebral dopamine neurotrophic factor (ARMET-like protein 1;Conserved dopamine neurotrophic factor)
- Background:
- CDNF (Cerebral Dopamine Neurotrophic Factor) is a Protein Coding gene. Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
- Subcellular Location:
- Secreted .
- Expression:
- Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.
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- Antibody-FAQs
- Products Images
- Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200