• Target：
• Neuropilin-2

• Gene Name：
• NRP2

• Protein Name：
• Neuropilin-2

• Human Gene Id：
• 8828

• Human Swiss Prot No：
• O60462

• Mouse Gene Id：
• 18187

• Mouse Swiss Prot No：
• O35375

• Rat Gene Id：
• 81527

• Rat Swiss Prot No：
• O35276

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2. AA range:791-840

• Specificity：
• Neuropilin-2 Polyclonal Antibody detects endogenous levels of Neuropilin-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NRP2;VEGF165R2;Neuropilin-2;Vascular endothelial cell growth factor 165 receptor 2

• Observed Band(KD)：
• 100kD

• Background：
• This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

• Function：
• function:High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.,similarity:Belongs to the neuropilin family.,similarity:Contains 1 MAM domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 F5/8 type C domains.,subunit:Heterodimer with NRP1 (Probable). Binds PLXNB1.,

• Subcellular Location：
• Membrane ; Single-pass type I membrane protein .; [Isoform s9]: Secreted .

• Expression：
• Brain,Human endometrium carcinoma cell line,Liver,Mammary gland,Ovary,Prostate adenocarcino

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