USP24 Polyclonal Antibody
- Catalog No.:YT4833
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- USP24
- Gene Name:
- USP24
- Protein Name:
- Ubiquitin carboxyl-terminal hydrolase 24
- Human Gene Id:
- 23358
- Human Swiss Prot No:
- Q9UPU5
- Mouse Gene Id:
- 329908
- Mouse Swiss Prot No:
- B1AY13
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human USP24. AA range:21-70
- Specificity:
- USP24 Polyclonal Antibody detects endogenous levels of USP24 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- USP24;KIAA1057;Ubiquitin carboxyl-terminal hydrolase 24;Deubiquitinating enzyme 24;Ubiquitin thioesterase 24;Ubiquitin-specific-processing protease 24
- Molecular Weight(Da):
- 211kD
- Background:
- Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
- Function:
- catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBA domain.,
- Subcellular Location:
- cytoplasm,
- Expression:
- Brain,Epithelium,Placenta,Platelet,T-cell,
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- Antibody-FAQs
- Products Images
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using USP24 Antibody. The picture on the right is blocked with the synthesized peptide.