• Target：
• TP53INP1

• Gene Name：
• TP53INP1

• Protein Name：
• Tumor protein p53-inducible nuclear protein 1

• Human Gene Id：
• 94241

• Human Swiss Prot No：
• Q96A56

• Mouse Swiss Prot No：
• Q9QXE4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TP53INP1. AA range:171-220

• Specificity：
• TP53INP1 Polyclonal Antibody detects endogenous levels of TP53INP1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TP53INP1;P53DINP1;SIP;Tumor protein p53-inducible nuclear protein 1;Stress-induced protein;p53-dependent damage-inducible nuclear protein 1;p53DINP1

• Observed Band(KD)：
• 27kD

• Background：
• function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,

• Function：
• function:In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.,induction:By adriamycin, gamma irradiation and H(2)O(2), in a p53-dependent way. At lower levels by ultraviolet irradiation.,subcellular location:Concentrated in PML/POD/ND10 nuclear bodies.,subunit:Interacts with TP53 and HIPK2.,tissue specificity:Ubiquitously expressed.,

• Subcellular Location：
• Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

• Expression：
• Ubiquitously expressed.

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