• Target：
• Synaptotagmin X

• Gene Name：
• SYT10

• Protein Name：
• Synaptotagmin-10

• Human Gene Id：
• 341359

• Human Swiss Prot No：
• Q6XYQ8

• Mouse Gene Id：
• 54526

• Mouse Swiss Prot No：
• Q9R0N4

• Rat Gene Id：
• 60567

• Rat Swiss Prot No：
• O08625

• Immunogen：
• Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460

• Specificity：
• Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SYT10;Synaptotagmin-10;Synaptotagmin X;SytX

• Observed Band(KD)：
• 55kD

• Background：
• cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,

• Function：
• cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,

• Subcellular Location：
• Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .

• Expression：
• Expressed only in pancreas, lung and kidney.

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