SMVT Polyclonal Antibody

    • Catalog No.:YT4349
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • SMVT
      • Fields:
      • >>Vitamin digestion and absorption
      • Gene Name:
      • SLC5A6
      • Protein Name:
      • Sodium-dependent multivitamin transporter
      • Human Gene Id:
      • 8884
      • Human Swiss Prot No:
      • Q9Y289
      • Mouse Swiss Prot No:
      • Q5U4D8
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human SLC5A6. AA range:551-600
      • Specificity:
      • SMVT Polyclonal Antibody detects endogenous levels of SMVT protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SLC5A6;SMVT;Sodium-dependent multivitamin transporter;Na(+)-dependent multivitamin transporter;Solute carrier family 5 member 6
      • Observed Band(KD):
      • 68kD
      • Background:
      • function:Transports pantothenate, biotin and lipoate in the presence of sodium.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.,
      • Function:
      • function:Transports pantothenate, biotin and lipoate in the presence of sodium.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.,
      • Subcellular Location:
      • Cell membrane ; Multi-pass membrane protein .; Cell membrane ; Multi-pass membrane protein . (Microbial infection) Exposure to E.coli lipopolysaccharides leeds to reduced cell membrane localization. .
      • Expression:
      • Expressed in microvessels of the brain (at protein level) (PubMed:25809983). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas (PubMed:10329687).
      • Products Images
      • Western blot analysis of lysates from HepG2 and HUVEC cells, using SLC5A6 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from COLO205 cells using SLC5A6 antibody.
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).