• Target：
• S-100A3

• Gene Name：
• S100A3

• Protein Name：
• Protein S100-A3

• Human Gene Id：
• 6274

• Human Swiss Prot No：
• P33764

• Mouse Gene Id：
• 20197

• Mouse Swiss Prot No：
• P62818

• Rat Gene Id：
• 114216

• Rat Swiss Prot No：
• P62819

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human S100A3. AA range:26-75

• Specificity：
• S-100A3 Polyclonal Antibody detects endogenous levels of S-100A3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• S100A3;S100E;Protein S100-A3;Protein S-100E;S100 calcium-binding protein A3

• Molecular Weight(Da)：
• 12kD

• Observed Band(KD)：
• 22kD

• Background：
• S100 calcium binding protein A3(S100A3) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008],

• Function：
• function:Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Skin specific.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Skin specific, specifically expressed at the inner endocuticle of hair fibers.

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