Rab 38 Polyclonal Antibody

    • Catalog No.:YT3933
    • Applications:WB;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Rab 38
      • Gene Name:
      • RAB38
      • Protein Name:
      • Ras-related protein Rab-38
      • Human Swiss Prot No:
      • P57729
      • Mouse Swiss Prot No:
      • Q8QZZ8
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129
      • Specificity:
      • Rab 38 Polyclonal Antibody detects endogenous levels of Rab 38 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC-p 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • RAB38;Ras-related protein Rab-38;Melanoma antigen NY-MEL-1
      • Observed Band(KD):
      • 26kD
      • Background:
      • function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes.,
      • Function:
      • function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes.,
      • Subcellular Location:
      • Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). .
      • Expression:
      • Expressed in melanocytes.
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, using RAB38 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).