• Target：
• p44S10

• Fields：
• >>Proteasome;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Epstein-Barr virus infection

• Gene Name：
• PSMD6

• Protein Name：
• 26S proteasome non-ATPase regulatory subunit 6

• Human Gene Id：
• 9861

• Human Swiss Prot No：
• Q15008

• Mouse Gene Id：
• 66413

• Mouse Swiss Prot No：
• Q99JI4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PSMD6. AA range:201-250

• Specificity：
• p44S10 Polyclonal Antibody detects endogenous levels of p44S10 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PSMD6;KIAA0107;PFAAP4;26S proteasome non-ATPase regulatory subunit 6;26S proteasome regulatory subunit RPN7;26S proteasome regulatory subunit S10;Breast cancer-associated protein SGA-113M;Phosphonoformate immuno-associated protein 4;

• Observed Band(KD)：
• 45kD

• Background：
• This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012],

• Function：
• function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit S10 family.,similarity:Contains 1 PCI domain.,subunit:Component of the PA700 complex.,

• Subcellular Location：
• proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle,proteasome accessory complex,extracellular exosome,

• Expression：
• Bone marrow,Lymph,Mammary cancer,Ovary,Placenta,Testis,

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