• Target：
• MCT12

• Gene Name：
• SLC16A12

• Protein Name：
• Monocarboxylate transporter 12

• Human Gene Id：
• 387700

• Human Swiss Prot No：
• Q6ZSM3

• Mouse Gene Id：
• 240638

• Mouse Swiss Prot No：
• Q8BGC3

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MOT12. AA range:115-164

• Specificity：
• MCT12 Polyclonal Antibody detects endogenous levels of MCT12 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SLC16A12;MCT12;Monocarboxylate transporter 12;MCT 12;Solute carrier family 16 member 12

• Observed Band(KD)：
• 53kD

• Background：
• This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010],

• Function：
• disease:Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.,function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.,similarity:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.,tissue specificity:Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Most highly expressed in kidney, followed by retina, lung, heart and testis. Very weakly expressed in brain and liver. Also detected in lens.

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