Maspin Polyclonal Antibody

    • Catalog No.:YT2657
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • Maspin
      • Fields:
      • >>p53 signaling pathway;>>MicroRNAs in cancer
      • Gene Name:
      • SERPINB5
      • Protein Name:
      • Serpin B5
      • Human Gene Id:
      • 5268
      • Human Swiss Prot No:
      • P36952
      • Mouse Swiss Prot No:
      • P70124
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140
      • Specificity:
      • Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • SERPINB5;PI5;Serpin B5;Maspin;Peptidase inhibitor 5;PI-5
      • Observed Band(KD):
      • 40kD
      • Background:
      • function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
      • Function:
      • function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
      • Subcellular Location:
      • Secreted, extracellular space.
      • Expression:
      • Normal mammary epithelial cells.
      • Products Images
      • Western Blot analysis of various cells using Maspin Polyclonal Antibody
      • Western blot analysis of lysates from HeLa cells, using Serpin B5 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from HeLa cells using PARP2 antibody.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).