• Target：
• MARCH3

• Gene Name：
• MARCH3

• Protein Name：
• E3 ubiquitin-protein ligase MARCH3

• Human Gene Id：
• 115123

• Human Swiss Prot No：
• Q86UD3

• Mouse Gene Id：
• 320253

• Mouse Swiss Prot No：
• Q8BRX9

• Rat Gene Id：
• 364878

• Rat Swiss Prot No：
• Q5XIE5

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MARCH3. AA range:111-160

• Specificity：
• MARCH3 Polyclonal Antibody detects endogenous levels of 40605 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• MARCH3;RNF173;E3 ubiquitin-protein ligase MARCH3;Membrane-associated RING finger protein 3;Membrane-associated RING-CH protein III;MARCH-III;RING finger protein 173

• Observed Band(KD)：
• 29kD

• Background：
• This gene encodes a member of the membrane-associated RING-CH (MARCH) family. The encoded protein is an E3 ubiquitin-protein ligase that may be involved in regulation of the endosomal transport pathway. [provided by RefSeq, Mar 2013],

• Function：
• domain:The RING-CH-type zinc finger domain is required for E3 ligase activity.,function:E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 RING-CH-type zinc finger.,subunit:Interacts with MARCH2 and STX6.,

• Subcellular Location：
• Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .

• Expression：
• Brain,Thalamus,

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