• Target：
• LRRK1

• Gene Name：
• LRRK1

• Protein Name：
• Leucine-rich repeat serine/threonine-protein kinase 1

• Human Gene Id：
• 79705

• Human Swiss Prot No：
• Q38SD2

• Mouse Swiss Prot No：
• Q3UHC2

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LRRK1. AA range:361-410

• Specificity：
• LRRK1 Polyclonal Antibody detects endogenous levels of LRRK1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LRRK1;KIAA1790;Leucine-rich repeat serine/threonine-protein kinase 1

• Molecular Weight(Da)：
• 228kD

• Background：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,

• Function：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Brain,Cervix,Lung,Macrophage,Pancreas,Skin,Spleen,

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