Gz-α Polyclonal Antibody

    • Catalog No.:YT2090
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat;Monkey
      • Target:
      • Gz-α
      • Fields:
      • >>Long-term depression
      • Gene Name:
      • GNAZ
      • Protein Name:
      • Guanine nucleotide-binding protein G(z) subunit alpha
      • Human Gene Id:
      • 2781
      • Human Swiss Prot No:
      • P19086
      • Mouse Swiss Prot No:
      • O70443
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human Gz-alpha. AA range:1-50
      • Specificity:
      • Gz-α Polyclonal Antibody detects endogenous levels of Gz-α protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • GNAZ;Guanine nucleotide-binding protein G(z) subunit alpha;G(x) alpha chain;Gz-alpha
      • Observed Band(KD):
      • 41kD
      • Background:
      • G protein subunit alpha z(GNAZ) Homo sapiens The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(i/o/t/z) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.,
      • Subcellular Location:
      • Membrane; Lipid-anchor.
      • Expression:
      • Brain,PNS,
      • Products Images
      • Western Blot analysis of various cells using Gz-α Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Gz-alpha Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from COS7 cells, treated with PMA 125ng/ml 30', using Gz-alpha Antibody. The lane on the right is blocked with the synthesized peptide.