• Target：
• Flt3-L

• Fields：
• >>MAPK signaling pathway;>>Ras signaling pathway;>>PI3K-Akt signaling pathway;>>Hematopoietic cell lineage;>>Pathways in cancer

• Gene Name：
• FLT3LG

• Protein Name：
• Fms-related tyrosine kinase 3 ligand

• Human Gene Id：
• 2323

• Human Swiss Prot No：
• P49771

• Mouse Swiss Prot No：
• P49772

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human Flt3 ligand. AA range:171-220

• Specificity：
• Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• FLT3LG;Fms-related tyrosine kinase 3 ligand;Flt3 ligand;Flt3L;SL cytokine

• Observed Band(KD)：
• 26kD

• Background：
• Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],

• Function：
• function:Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins.,subunit:Homodimer (isoform 2).,

• Subcellular Location：
• [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.

• Expression：
• Brain,Spleen,

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