ELOVL1 Polyclonal Antibody

    • Catalog No.:YT1535
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • ELOVL1
      • Fields:
      • >>Fatty acid elongation;>>Biosynthesis of unsaturated fatty acids;>>Metabolic pathways;>>Fatty acid metabolism
      • Gene Name:
      • ELOVL1
      • Protein Name:
      • Elongation of very long chain fatty acids protein 1
      • Human Swiss Prot No:
      • Q9BW60
      • Mouse Swiss Prot No:
      • Q9JLJ5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human ELOVL1. AA range:101-150
      • Specificity:
      • ELOVL1 Polyclonal Antibody detects endogenous levels of ELOVL1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ELOVL1;SSC1;CGI-88;Elongation of very long chain fatty acids protein 1;3-keto acyl-CoA synthase ELOVL1;ELOVL fatty acid elongase 1;ELOVL FA elongase 1
      • Observed Band(KD):
      • 33kD
      • Background:
      • domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
      • Function:
      • domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
      • Subcellular Location:
      • Endoplasmic reticulum membrane ; Multi-pass membrane protein .
      • Expression:
      • Ubiquitous.
      • Products Images
      • Western Blot analysis of various cells using ELOVL1 Polyclonal Antibody diluted at 1:1000
      • Immunohistochemical analysis of paraffin-embedded Human skeletal muscle. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Western blot analysis of lysates from Jurkat and HepG2 cells, using ELOVL1 Antibody. The lane on the right is blocked with the synthesized peptide.