• Target：
• Connexin 25

• Gene Name：
• GJB7

• Protein Name：
• Gap junction beta-7 protein

• Human Gene Id：
• 375519

• Human Swiss Prot No：
• Q6PEY0

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70

• Specificity：
• Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• GJB7;CX25;Gap junction beta-7 protein;Connexin-25;Cx25

• Observed Band(KD)：
• 24kD

• Background：
• Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],

• Function：
• function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .

• Expression：
• Weakly expressed in placenta.

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