• Target：
• CKR-2

• Gene Name：
• CCR2

• Protein Name：
• C-C chemokine receptor type 2

• Human Swiss Prot No：
• P41597

• Mouse Gene Id：
• 12772

• Rat Gene Id：
• 60463

• Rat Swiss Prot No：
• O55193

• Immunogen：
• Synthesized peptide derived from CKR-2 . at AA range: 250-330

• Specificity：
• CKR-2 Polyclonal Antibody detects endogenous levels of CKR-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CCR2;CMKBR2;C-C chemokine receptor type 2;C-C CKR-2;CC-CKR-2;CCR-2;CCR2;Monocyte chemoattractant protein 1 receptor;MCP-1-R;CD antigen CD192

• Observed Band(KD)：
• 46kD

• Background：
• CCR2 (C-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CCR2 include idiopathic anterior uveitis and cd3zeta deficiency. Among its related pathways are Signaling by GPCR and A-beta Pathways: uptake and Degradation. GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity. An important paralog of this gene is CCR9. eceptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection. hemokine CC receptors (CCRs) predominantly recognize CC chemokines. CC chemokines are distinguished by having four conserved cysteines, with the first two cysteines being adjacent to each other. There are 10 chemokine CC receptors.

Identification of CCR2 as a hub in septic myocardial injury and cardioprotection of silibinin FREE RADICAL BIOLOGY AND MEDICINE Ye Tian WB Mouse cardiomyocytes

Synergistic reinforcement of immunogenic cell death and transformation of tumor-associated macrophages via an M1-type macrophage membrane-camouflaged ferrous-supply-regeneration nanoplatform Acta Biomaterialia Yuemin Wang WB Mouse K7 cell,RAW264.7 cell

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