• Target：
• CCS

• Fields：
• >>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases

• Gene Name：
• CCS

• Protein Name：
• Copper chaperone for superoxide dismutase

• Human Gene Id：
• 9973

• Human Swiss Prot No：
• O14618

• Mouse Swiss Prot No：
• Q9WU84

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human CCS. AA range:225-274

• Specificity：
• CCS Polyclonal Antibody detects endogenous levels of CCS protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CCS;Copper chaperone for superoxide dismutase;Superoxide dismutase copper chaperone

• Observed Band(KD)：
• 32kD

• Background：
• Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008],

• Function：
• cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 2 copper ions per subunit.,function:Delivers copper to copper zinc superoxide dismutase (SOD1).,similarity:Contains 1 HMA domain.,similarity:In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.,subunit:Homodimer, and heterodimer with SOD1.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Cytoplasm .

• Expression：
• Ubiquitous.

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