Calpain 11 Polyclonal Antibody

    • Catalog No.：YT0615
    • Applications：WB;ELISA
    • Reactivity：Human;Rat;Mouse;
      • Target：
      • Calpain 11
      • Gene Name：
      • CAPN11
      • Protein Name：
      • Calpain-11
      • Human Swiss Prot No：
      • Q9UMQ6
      • Mouse Swiss Prot No：
      • Q6J756
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human CAPN11. AA range:401-450
      • Specificity：
      • Calpain 11 Polyclonal Antibody detects endogenous levels of Calpain 11 protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • CAPN11;Calpain-11;Calcium-activated neutral proteinase 11;CANP 11
      • Observed Band(KD)：
      • 81kD
      • Background：
      • Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008],
      • Function：
      • catalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 2 EF-hand domains.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,tissue specificity:Highest expression in testis.,
      • Subcellular Location：
      • Cytoplasmic vesicle, secretory vesicle, acrosome .
      • Expression：
      • Highest expression in testis.
      • Products Images
      • Western Blot analysis of various cells using Calpain 11 Polyclonal Antibody

      Attributes

      • Code：
      • YT0615
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-07-19
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