• Target：
• L-type Ca++ CP γ4

• Fields：
• >>MAPK signaling pathway;>>Cardiac muscle contraction;>>Adrenergic signaling in cardiomyocytes;>>Oxytocin signaling pathway;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy

• Gene Name：
• CACNG4

• Protein Name：
• Voltage-dependent calcium channel gamma-4 subunit

• Human Gene Id：
• 27092

• Human Swiss Prot No：
• Q9UBN1

• Mouse Swiss Prot No：
• Q9JJV4

• Rat Swiss Prot No：
• Q8VHW9

• Immunogen：
• Synthetic Peptide of L-type Ca++ CP γ4 AA range: 120-200

• Specificity：
• The antibody detects endogenous L-type Ca++ CP γ4 protein.

• Formulation：
• PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:1000-2000 IHC 1:200-500. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CACNG4;Voltage-dependent calcium channel gamma-4 subunit;Neuronal voltage-gated calcium channel gamma-4 subunit;Transmembrane AMPAR regulatory protein gamma-4;TARP gamma-4

• Observed Band(KD)：
• 35kD

• Background：
• calcium voltage-gated channel auxiliary subunit gamma 4(CACNG4) Homo sapiens The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],

• Function：
• function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Detected in heart left ventricle.

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