• Target：
• Mas1

• Fields：
• >>Neuroactive ligand-receptor interaction;>>Renin-angiotensin system;>>Coronavirus disease - COVID-19

• Gene Name：
• MAS1

• Protein Name：
• Proto-oncogene Mas

• Human Gene Id：
• 4142

• Human Swiss Prot No：
• P04201

• Mouse Swiss Prot No：
• P30554

• Rat Swiss Prot No：
• P12526

• Immunogen：
• Synthetic Peptide of Mas1

• Specificity：
• The antibody detects endogenous Mas1 protein.

• Formulation：
• PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:2000-5000 IHC 1:200-500. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• MAS1;MAS;Proto-oncogene Mas

• Observed Band(KD)：
• 36-50kD

• Background：
• This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012],

• Function：
• caution:Was originally (PubMed:3419518) thought to be a receptor for angiotensin II.,disease:The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

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