• Target：
• BKRB2

• Fields：
• >>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Sphingolipid signaling pathway;>>Neuroactive ligand-receptor interaction;>>Complement and coagulation cascades;>>Inflammatory mediator regulation of TRP channels;>>Regulation of actin cytoskeleton;>>Endocrine and other factor-regulated calcium reabsorption;>>Chagas disease;>>Pathways in cancer

• Gene Name：
• BDKRB2 BKR2

• Protein Name：
• B2 bradykinin receptor (B2R) (BK-2 receptor)

• Human Gene Id：
• 624

• Human Swiss Prot No：
• P30411

• Mouse Swiss Prot No：
• P32299

• Rat Swiss Prot No：
• P25023

• Immunogen：
• Synthesized peptide derived from human protein . at AA range: 140-220

• Specificity：
• BKRB2 Polyclonal Antibody detects endogenous levels of protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000 ELISA 1:5000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Observed Band(KD)：
• 43kD

• Background：
• This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008],

• Function：
• function:Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Ubiquitous. Widespread in normal smooth muscle tissue and neurons.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Ubiquitous. Widespread in normal smooth muscle tissue and neurons.

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