CD2 Monoclonal Antibody(3F3)

    • Catalog No.:YM3069
    • Applications:IHC;IF
    • Reactivity:Human;Mouse;Rat
      • Target:
      • CD2
      • Fields:
      • >>Cell adhesion molecules;>>Hematopoietic cell lineage
      • Gene Name:
      • CD2
      • Protein Name:
      • T-cell surface antigen CD2
      • Human Gene Id:
      • 914
      • Human Swiss Prot No:
      • P06729
      • Mouse Swiss Prot No:
      • P08920
      • Immunogen:
      • Synthetic Peptide of CD2
      • Specificity:
      • The antibody detects endogenous CD2 proteins.
      • Formulation:
      • PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
      • Source:
      • Monoclonal, Mouse
      • Dilution:
      • IHC 1:200. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CD2;SRBC;T-cell surface antigen CD2;Erythrocyte receptor;LFA-2;LFA-3 receptor;Rosette receptor;T-cell surface antigen T11/Leu-5;CD2
      • Molecular Weight(Da):
      • 39kD
      • Background:
      • The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],
      • Function:
      • function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,
      • Subcellular Location:
      • Cell membrane ; Single-pass type I membrane protein .
      • Expression:
      • Expressed in natural killer cells (at protein level).
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded Human-colon tissue. 1,CD2 Monoclonal Antibody(3F3) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.
      • Immunohistochemical analysis of paraffin-embedded Rat-spleen tissue. 1,CD2 Monoclonal Antibody(3F3) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.
      • Immunohistochemical analysis of paraffin-embedded Mouse-spleen tissue. 1,CD2 Monoclonal Antibody(3F3) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.
      • Immunohistochemical analysis of paraffin-embedded Human Tonsil Caricnoma using CD2 Mouse mAb diluted at 1:500.