• Target：
• RECQ5

• Gene Name：
• RECQL5 RECQ5

• Protein Name：
• RECQ5

• Human Gene Id：
• 9400

• Human Swiss Prot No：
• O94762

• Immunogen：
• Synthesized peptide derived from human RECQ5 AA range: 647-697

• Specificity：
• This antibody detects endogenous levels of RECQ5 at Human

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 109kD

• Background：
• The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],

• Function：
• function:May have an important role in DNA metabolism.,similarity:Belongs to the helicase family. RecQ subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with TOP3A and TOP3B.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• [Isoform Beta]: Nucleus, nucleoplasm . Nucleus . Recruited to sites of DNA damage, such as single-strand breaks and inter-strand cross-links, and at stalled replication forks. Re-localizes from the nucleolus into the nucleus after replicative stress and significantly associates with WRN during S-phase (PubMed:23180761). .; [Isoform Alpha]: Cytoplasm .; [Isoform Gamma]: Cytoplasm .

• Expression：
• Ubiquitous.

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