SDHL rabbit pAb

    • Catalog No.:YT7040
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • SDHL
      • Fields:
      • >>Glycine, serine and threonine metabolism;>>Cysteine and methionine metabolism;>>Valine, leucine and isoleucine biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids
      • Gene Name:
      • SDS SDH
      • Protein Name:
      • SDHL
      • Human Swiss Prot No:
      • P20132
      • Mouse Swiss Prot No:
      • Q8VBT2
      • Immunogen:
      • Synthesized peptide derived from human SDHL AA range: 207-257
      • Specificity:
      • This antibody detects endogenous levels of SDHL at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 36kD
      • Background:
      • This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008],
      • Function:
      • catalytic activity:L-serine = pyruvate + NH(3).,cofactor:Pyridoxal phosphate.,pathway:Carbohydrate biosynthesis; gluconeogenesis.,similarity:Belongs to the serine/threonine dehydratase family.,subunit:Homodimer.,
      • Subcellular Location:
      • Cytoplasm.
      • Products Images
      • Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).