NAT8L rabbit pAb

    • Catalog No.:YT6692
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • NAT8L
      • Fields:
      • >>Alanine, aspartate and glutamate metabolism;>>Metabolic pathways
      • Gene Name:
      • NAT8L CML3
      • Protein Name:
      • NAT8L
      • Human Swiss Prot No:
      • Q8N9F0
      • Mouse Swiss Prot No:
      • Q3UGX3
      • Immunogen:
      • Synthesized peptide derived from human NAT8L AA range: 218-268
      • Specificity:
      • This antibody detects endogenous levels of NAT8L at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 33kD
      • Background:
      • This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010],
      • Function:
      • similarity:Belongs to the camello family.,similarity:Contains 1 N-acetyltransferase domain.,
      • Subcellular Location:
      • Cytoplasm . Microsome membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. .
      • Expression:
      • Expressed in brain.
      • Products Images
      • Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).