NAT8L rabbit pAb
- Catalog No.:YT6692
- Applications:WB;ELISA;IHC
- Reactivity:Human;Mouse;Rat
- Target:
- NAT8L
- Fields:
- >>Alanine, aspartate and glutamate metabolism;>>Metabolic pathways
- Gene Name:
- NAT8L CML3
- Protein Name:
- NAT8L
- Human Gene Id:
- 339983
- Human Swiss Prot No:
- Q8N9F0
- Mouse Gene Id:
- 269642
- Mouse Swiss Prot No:
- Q3UGX3
- Rat Gene Id:
- 289727
- Rat Swiss Prot No:
- D3ZVU9
- Immunogen:
- Synthesized peptide derived from human NAT8L AA range: 218-268
- Specificity:
- This antibody detects endogenous levels of NAT8L at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 33kD
- Background:
- This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010],
- Function:
- similarity:Belongs to the camello family.,similarity:Contains 1 N-acetyltransferase domain.,
- Subcellular Location:
- Cytoplasm . Microsome membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. .
- Expression:
- Expressed in brain.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).