• Target：
• MECR

• Fields：
• >>Fatty acid biosynthesis;>>Fatty acid elongation;>>Metabolic pathways;>>Fatty acid metabolism

• Gene Name：
• MECR NBRF1 CGI-63

• Protein Name：
• MECR

• Human Gene Id：
• 51102

• Human Swiss Prot No：
• Q9BV79

• Mouse Gene Id：
• 26922

• Mouse Swiss Prot No：
• Q9DCS3

• Rat Gene Id：
• 29470

• Rat Swiss Prot No：
• Q9Z311

• Immunogen：
• Synthesized peptide derived from human MECR AA range: 160-210

• Specificity：
• This antibody detects endogenous levels of MECR at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1：500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 41kD

• Function：
• catalytic activity:Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.,function:Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Homodimer.,tissue specificity:Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.,

• Subcellular Location：
• [Isoform 1]: Mitochondrion .; [Isoform 2]: Cytoplasm . Nucleus .

• Expression：
• Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.

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