• Target：
• MYT1L

• Gene Name：
• MYT1L KIAA1106

• Protein Name：
• MYT1L

• Human Gene Id：
• 23040

• Human Swiss Prot No：
• Q9UL68

• Mouse Swiss Prot No：
• P97500

• Rat Gene Id：
• 116668

• Rat Swiss Prot No：
• P70475

• Immunogen：
• Synthesized peptide derived from human MYT1L AA range: 595-645

• Specificity：
• This antibody detects endogenous levels of MYT1L at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 130kD

• Background：
• This gene encodes a member of the zinc finger superfamily of transcription factors. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016],

• Function：
• function:May function as a panneural transcription factor associated with neuronal differentiation. May play a role in the development of neurons and oligodendrogalia in the CNS.,similarity:Contains 6 C2HC-type zinc fingers.,

• Subcellular Location：
• Nucleus . Chromosome . Preferentially binds to DNA binding sites that are in an open chromatin configuration. .

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