FBX46 rabbit pAb
- Catalog No.:YT6334
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- FBX46
- Gene Name:
- FBXO46 FBX46 FBXO34L
- Protein Name:
- FBX46
- Human Gene Id:
- 23403
- Human Swiss Prot No:
- Q6PJ61
- Mouse Gene Id:
- 243867
- Mouse Swiss Prot No:
- Q8BG80
- Rat Gene Id:
- 292686
- Rat Swiss Prot No:
- Q4KLY2
- Immunogen:
- Synthesized peptide derived from human FBX46 AA range: 67-117
- Specificity:
- This antibody detects endogenous levels of FBX46 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 66kD
- Background:
- Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],
- Function:
- caution:The region from 1 to 163 was deduced from the genomic sequence and ESTs by similarity to the mouse sequence.,function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,subunit:Interacts with SKP1A and CUL1.,
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- Products Images
- Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night