• Target：
• PSAP

• Gene Name：
• ACP3

• Protein Name：
• Prostatic Acid Phosphatase(PSAP)

• Human Gene Id：
• 3662

• Human Swiss Prot No：
• P15309

• Immunogen：
• Synthesized peptide derived from human Prostatic Acid Phosphatase(PSAP) AA range:201-300

• Specificity：
• This antibody detects endogenous levels of PSAP

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Monoclonal, Rabbit IgG1, Kappa

• Dilution：
• IHC 1:100-500, ELISA 1:5000-20000

• Purification：
• Recombinant Expression and Affinity purified

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• 5' NT;5' nucleotidase;5'-NT;5'-nucleotidase;Acid phosphatase prostate;ACP 3;ACP3;acpP;Ecto 5' nucleotidase;Ecto-5'-nucleotidase;PAP;PPAP_HUMAN;Prostatic acid phosphatase;Prostatic acid phosphotase;Thiamine monophosphatase;TMPase

• Function：
• catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,similarity:Belongs to the histidine acid phosphatase family.,subcellular location:Predominantly localized in the plasma membrane but also detected in intracellular vesicles.,subunit:Homodimer.,

• Subcellular Location：
• [Isoform 1]: Secreted .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Nucleus . Cytoplasm, cytosol . Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319). .

• Expression：
• Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Low expression in prostate carcinoma cells and tissues. ; [Isoform 2]: Widely expressed. Expressed in the sarcolemma of skeletal muscle.

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