ADX rabbit pAb

  • Catalog No.：YT8131
  • Applications：IHC;WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • FDX1
    • Gene Name：
    • FDX1 ADX
    • Protein Name：
    • Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
    • Human Gene Id：
    • 2230
    • Human Swiss Prot No：
    • P10109
    • Mouse Swiss Prot No：
    • P46656
    • Immunogen：
    • Synthesized peptide derived from human N-ternal ADX
    • Specificity：
    • This antibody detects endogenous levels of ADX at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 IHC 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
    • Molecular Weight(Da)：
    • 20kD
    • Function：
    • Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
    • Subcellular Location：
    • Mitochondrion matrix .
    • Expression：
    • Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

    Attributes

    • Code：
    • YT8131
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 160 / 280 / 450
    • Delivery：
    • 2024-07-25
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