OGDHL rabbit pAb

  • Catalog No.:YT8128
  • Applications:IHC;WB
  • Reactivity:Human
    • Target:
    • OGDHL
    • Gene Name:
    • OGDHL KIAA1290
    • Protein Name:
    • 2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.-) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)
    • Human Swiss Prot No:
    • Q9ULD0
    • Immunogen:
    • Synthesized peptide derived from human C-ternal OGDHL
    • Specificity:
    • This antibody detects endogenous levels of OGDHL at Human
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000 IHC 1:50-200
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • 2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.-) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)
    • Molecular Weight(Da):
    • 111kD
    • Function:
    • 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH (By similarity). The OGDHC complex is mainly active in the mitochondrion (By similarity). Involved in the inhibition of cell proliferation and in apoptosis .
    • Subcellular Location:
    • Mitochondrion matrix .
    • Expression:
    • Expressed in the brain and the liver.