P2RX7 rabbit pAb

  • Catalog No.：YT8119
  • Applications：IHC;WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • P2RX7
    • Gene Name：
    • P2RX7
    • Protein Name：
    • P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
    • Human Gene Id：
    • 5027
    • Human Swiss Prot No：
    • Q99572
    • Mouse Swiss Prot No：
    • Q9Z1M0
    • Immunogen：
    • Synthesized peptide derived from human C-ternal P2RX7
    • Specificity：
    • This antibody detects endogenous levels of P2RX7 at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000 IHC 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
    • Molecular Weight(Da)：
    • 65kD
    • Function：
    • Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells .
    • Subcellular Location：
    • Cell membrane ; Multi-pass membrane protein .
    • Expression：
    • Widely expressed with highest levels in brain and immune tissues.

    Attributes

    • Code：
    • YT8119
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 160 / 280 / 450
    • Delivery：
    • 2024-11-26
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