SIPA1 rabbit pAb
- Catalog No.:YT8114
- Applications:IHC;WB
- Reactivity:Human;Mouse
- Target:
- SIPA1
- Gene Name:
- SIPA1 SPA1
- Protein Name:
- Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)
- Human Gene Id:
- 6494
- Human Swiss Prot No:
- Q96FS4
- Mouse Swiss Prot No:
- P46062
- Immunogen:
- Synthesized peptide derived from human N-ternal SIPA1
- Specificity:
- This antibody detects endogenous levels of SIPA1 at Human, Mouse
- Formulation:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000 IHC 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)
- Molecular Weight(Da):
- 115kD
- Function:
- GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state . Affects cell cycle progression (By similarity).
- Subcellular Location:
- Nucleus . Cytoplasm, perinuclear region . Endomembrane system; Peripheral membrane protein . Mostly localized in the perinuclear membraneous region. .
- Expression:
- Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
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