SIPA1 rabbit pAb

  • Catalog No.:YT8114
  • Applications:IHC;WB
  • Reactivity:Human;Mouse
    • Target:
    • SIPA1
    • Gene Name:
    • SIPA1 SPA1
    • Protein Name:
    • Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)
    • Human Gene Id:
    • 6494
    • Human Swiss Prot No:
    • Q96FS4
    • Mouse Swiss Prot No:
    • P46062
    • Immunogen:
    • Synthesized peptide derived from human N-ternal SIPA1
    • Specificity:
    • This antibody detects endogenous levels of SIPA1 at Human, Mouse
    • Formulation:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000 IHC 1:50-200
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1) (p130 SPA-1)
    • Molecular Weight(Da):
    • 115kD
    • Function:
    • GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state . Affects cell cycle progression (By similarity).
    • Subcellular Location:
    • Nucleus . Cytoplasm, perinuclear region . Endomembrane system; Peripheral membrane protein . Mostly localized in the perinuclear membraneous region. .
    • Expression:
    • Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.